The religious Guesthouse in Rome, bed & breakfast service, Residenza Spirito Santo recently renovated updated. Open all-year-round 24/7. A few minutes walk from the Vatican, easily reachable by metro (FL3) from St. Peter’s to Gemelli station. Next to the Catholic University of the Sacro Cuore, the Gemelli general hospital, the astronomical observatory and the Monte Mario nature reserve with an extensive cycle path which leads to the Valle Aurelia metro station.

The religious Guesthouse Residenza Spirito Santo offers international standards and quality services combined with Italian hospitality. Every morning our generous breakfast is served from 7.00 to 9.30 to give you a great awakening. Homemade cakes, croissants, jams, cereals, biscuits, fresh fruit, yoghurt, cold meats and cheeses to be accompanied by tea, fruit juice, cappuccino, chocolate and coffee. In addition, upon request, gluten and lactose free products are available.

The Residenza Spirito Santo has modern rooms with Marazzi ceramic floors which ensure cleanliness and comfort. Wi-Fi is free throughout the area.  Choose our hotel and you will enjoy comfortable accommodation in a religious Guesthouse to visit the Vatican museums and the main tourist attractions of Rome.

Some of our services

For the added pleasure of our guests, drinks and snacks are served at the bar-lounge, on the wonderful sun terrace with views of the beautiful garden with centuries-old trees.

54 comfortable & functional non-smoking en-suite bedrooms (singles, doubles and family units) all of them sound-proofed, equipped to the highest standards. Each room with private facilities, shower, bed and bathroom linen, hair & body-lotions kit, hairdryer, small refrigerator with quite small freezer, individually controlled heating & air-conditioning, TV colour, fast internet cable access and WI FI; some rooms overlook the beautiful garden with its rich orchard and centuries-old trees.Lifts serve all floors.


  • Air conditioning
  • Wi-fi in all areas
  • Healthy and generous breakfast
  • Coffee shop
  • Lounge-bar & catering service
  • Garden equipped with tables and comfy chairs
  • Sun terrace
  • Private chapel 
  • 2 lifts
  • Large car park for cars and coaches. 

No pets allowed